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ERalpha signals through classical estrogen response element (ERE)-dependent genomic as well as nonclassical ERE-independent genomic and nongenomic pathways. Vascular endothelial growth factor (VEGF) plays multifunctional roles in vascular permeability, repair and remodelling processes, in addition to the maintenance of vascular structure and function. In addition, in women given the diagnosis of melanoma during or within 1 year after childbirth, regular follow-up and viagra or cialis monitoring for recurrence are recommended.

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